{"id":57757,"date":"2023-06-28T23:54:34","date_gmt":"2023-06-28T23:54:34","guid":{"rendered":"https:\/\/purmabiologics.com\/blog\/?post_type=product&#038;p=57757"},"modified":"2026-07-24T15:22:52","modified_gmt":"2026-07-24T21:22:52","slug":"penicillin-streptomycin-antibiotic-mix","status":"publish","type":"product","link":"https:\/\/purmabiologics.com\/blog\/product\/penicillin-streptomycin-antibiotic-mix\/","title":{"rendered":"Penicillin\/Streptomycin Antibiotic Mix (100X)"},"content":{"rendered":"<h2>Background<\/h2>\n<p>PurMa\u2122 Penicillin\/Streptomycin Antibiotic Mix (100X) contains all the necessary ingredients which successfully prevent common contaminants.<\/p>\n<p>In mammalian cell culture, we always need to prevent\u00a0 contamination of four types of contaminants which most of the cell lines need to overcome : Bacterial contamination, mold &amp; virus contamination, mycoplasma contamination, as well as yeast contamination. Commonly, most of the cell lines, unless they are maintained fully aseptic and come from an aseptic facility, need a mixture of antibiotics to prevent above-mentioned contaminants. PurMa<sup>TM<\/sup> Penicillin\/ Streptomycin Mix contains<\/p>\n<p><strong>Ingredients<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"155\">Streptomycin<\/td>\n<td width=\"174\">10 mg\/mL<\/td>\n<\/tr>\n<tr>\n<td width=\"155\">Penicillin<\/td>\n<td width=\"174\">10000 UI\/mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Features and benefits:<\/strong><\/p>\n<ul>\n<li>Cost effective!<\/li>\n<li>Effectively removes both gram-positive and gram-negative bacteria.<\/li>\n<li>Moreover, it contains antibiotics and antimycotics to prevent yeast and mycoplasma partially. PurMa Biologics, however, manufactures PurMa\u2122 Mycoplasma Treatment Kit (MTK) (100X)\u00a0 (Cat:<span class=\"sku_wrapper\"><span class=\"sku\" data-o_content=\"N\/A\">P5M010408<\/span><\/span>) which successfully eliminates mycoplasma from cell culture without harming most of the cell lines.<\/li>\n<li>Does not harm a healthy cell line if it is used in the recommended concentration.<\/li>\n<li>Finally, we highly recommend performing a dose-response test at the beginning to decide the level in which the contamination is prevented and, importantly, the cultured cells and tissues are in their high-performance<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Formulation<\/h2>\n<p>Please find the formulation here :<a href=\"https:\/\/purmabiologics.com\/blog\/wp-content\/uploads\/2024\/10\/PurMa\u2122-Penicillin_Streptomycin_100X.pdf\"><strong><span style=\"color: #0000ff;\">Formulation<\/span><\/strong><\/a><\/p>\n<h2>References<\/h2>\n<ol>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20983031\/\" rel=\"nofollow noopener\" target=\"_blank\"><span style=\"color: #0000ff;\">Antibacterial action of penicillin, penicillin X, and streptomycin on Hemophilus influenzae.<\/span> <\/a>HEWITT WL, PITTMAN M. Public Health Rep (1896). 1946 May 31;61:768-78. PMID: 20983031.<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3644854\/\" rel=\"nofollow noopener\" target=\"_blank\"><span style=\"color: #0000ff;\">In vitro and in vivo studies of streptomycin-resistant, penicillin-susceptible streptococci from patients with infective endocarditis.<\/span> <\/a>Enzler MJ, Rouse MS, Henry NK, Geraci JE, Wilson WR. J Infect Dis. 1987 May;155(5):954-8. doi: 10.1093\/infdis\/155.5.954. PMID: 3644854.<\/li>\n<\/ol>\n<p><strong>Learn more:<\/strong> <a href=\"\/what-is-penicillin-streptomycin\/\">What Is Pen-Strep?<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Penicillin\/Streptomycin Antibiotic Mix (100X) prevents bacterial, mold &amp; virus as well as yeast and to some extent mycoplasma . Moreover, most of the cell lines, unless they are maintained fully aseptic and come from an aseptic facility, need a mixture of antibiotics to prevent various above-mentioned contamination.<\/p>\n","protected":false},"featured_media":123634,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[33],"product_tag":[636,637,638,571,635,633,634,639,640],"class_list":["post-57757","product","type-product","status-publish","has-post-thumbnail","product_cat-cell-culture-suited-antibiotics","product_tag-antibiotic-mix-solution","product_tag-bacterial","product_tag-mold","product_tag-mycoplasma","product_tag-neomycin","product_tag-penicillin","product_tag-streptomycin","product_tag-virus","product_tag-yeast","entry","has-media","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-variable","has-product-nav","col","span_1_of_4","owp-content-center","owp-thumbs-layout-horizontal","owp-btn-normal","owp-tabs-layout-horizontal","has-no-thumbnails"],"acf":[],"_links":{"self":[{"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/product\/57757","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/comments?post=57757"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/media\/123634"}],"wp:attachment":[{"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/media?parent=57757"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/product_brand?post=57757"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/product_cat?post=57757"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/purmabiologics.com\/blog\/wp-json\/wp\/v2\/product_tag?post=57757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}