Ultra-Premium\u00a0 PurMa\u2122 Fetal Bovine Serum (UP-FBS) is the result of more than three decades of focused work in protein biochemistry. Leveraging this expertise, PurMa Biologics has developed a true next-generation serum. Ultra-Premium Fetal Bovine Serum (UP-FBS) is specifically engineered to deliver higher potency and performance than any other fetal bovine serum currently on the market, while maintaining exceptional lot-to-lot consistency.<\/p>\n
In many in vitro cell culture studies, batch-wise variations in biological materials, especially serum, are a major source of experimental variability. Ultra-Premium PurMa\u2122 Fetal Bovine Serum (UP-FBS) is manufactured, purified, and evaluated to minimize these fluctuations, thereby improving reproducibility in cell-based assays, biomarker studies, and bioproduction workflows. A key factor in the quality of UP-FBS is stringent control over the age and origin of the fetus, which directly influences growth factor composition, protein profile, and overall serum performance. Nowadays, premium imported fetal bovine serum has become popular among laboratories due to its affordable price, even though it does not offer the quality that provides enough potency.<\/p>\n
Not sure which serum fits your cells? See our complete guide to\u00a0cell culture serum.<\/a><\/p>\n Ultra-Premium PurMa\u2122 Fetal Bovine Serum (UP-FBS) is:<\/strong><\/p>\n Through this approach, Ultra-Premium PurMa\u2122 Fetal Bovine Serum (UP-FBS) delivers superior cell growth, enhanced viability, and improved consistency across experiments when compared with conventional fetal bovine serum products.<\/p>\n \u00a0Major Differences Between bovine serum premium research grade and UP-FBS<\/strong><\/p>\n Ultra-Premium\u00a0 PurMa\u2122 Fetal Bovine Serum (UP-FBS) is distinguished from PurMa\u2122 fetal bovine serum premium :<\/p>\n Source of the Blood<\/strong><\/p>\n 1. P-FBS is derived from more stringently selected fetal bovine sources, including tighter control of fetal age and collection conditions.<\/p>\n 2. This refined sourcing leads to significantly higher cell growth and more robust performance of Ultra-Premium PurMa\u2122\u00a0 Fetal Bovine Serum (UP-FBS) compared with P-FBS in a wide range of cell lines and culture conditions.<\/p>\n Depth of Analytical Characterization<\/strong><\/p>\n 1. Ultra-Premium PurMa\u2122 Fetal Bovine Serum (UP-FBS) undergoes an expanded analytical panel and enhanced quality control relative to standard P-FBS<\/p>\n 2. This deeper analysis allows tighter specification ranges, improved lot qualification, and greater reproducibility of results.<\/p>\n The analytical foundation established with P-FBS is further refined and expanded for Ultra-Premium Fetal Bovine Serum (UP-FBS), enabling even more precise control over serum composition and performance.<\/p>\n Ultra-Premium PurMa\u2122 Fetal Bovine Serum (UP-FBS) goes through a detailed analysis. Here is an example of how we analyze this serum:Routine Pathological Analysis on PurMa Bovine and Horse Serums<\/span><\/a><\/strong><\/p>\n \n\n
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\n Methodology<\/strong><\/td>\n Unit measured<\/strong><\/td>\n Accepted level<\/strong><\/td>\n Result<\/strong><\/td>\n<\/tr>\n \n Sterility (Current USP and EP 2.6.1 for Bacteria & Fungi)<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n pH<\/td>\n N\/A<\/td>\n measured<\/td>\n 6.58<\/td>\n<\/tr>\n \n Osmolality (USP 785)\u00a0\u00a0\u00a0\u00a0 mOsm\/KgH2<\/td>\n mOsm\/KgH20<\/td>\n 280-340<\/td>\n 288<\/td>\n<\/tr>\n \n Hemoglobin (Fleming & Woolf)<\/td>\n mg\/dL<\/td>\n <25<\/td>\n 12.9<\/td>\n<\/tr>\n \n Endotoxin (USP 85)<\/td>\n EU\/mL<\/td>\n <20<\/td>\n <0.100<\/td>\n<\/tr>\n \n Mycoplasma (Barile & Kern; Large Volume, Direct Culture)<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n IgG<\/td>\n Elliza<\/td>\n Measured<\/td>\n 0.09 ug\/ml<\/td>\n<\/tr>\n \n Albumin<\/td>\n Eliza<\/td>\n Measured<\/td>\n \u2264 4.6 g\/dL<\/td>\n<\/tr>\n \n Virus Testing (9 CFR 113.53c)<\/strong><\/td>\n <\/td>\n <\/td>\n <\/td>\n<\/tr>\n \n Bovine Adenovirus<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Bovine Parvovirus<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Bovine Respiratory Syncytial Virus<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Bovine Viral Diarrhea Virus<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Rabies<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Reovirus<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Cytopathogenic Agents (IBR)<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Hemadsorbing Agents (PI3)<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n \n Bluetongue<\/td>\n NA<\/td>\n Not Detected<\/td>\n Not Detected<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n