Although Iscove’s Modified Dulbecco’s Medium (IMDM) is specialized for rapidly proliferating cell lines, it is certainly quite suitable for slow-growing cells as well. Moreover, this medium is the only medium that lacks Iron, with potassium nitrate replacing ferric nitrate, therefore making it an excellent choice for adhesive cells.
scove’s Modified Dulbecco’s Medium (IMDM) is specialized for rapidly proliferating, high-density cell lines. Therefore, it is excellent for Jurkat, Hek, COS-7, and macrophage cells. IMDM is a modified and more advanced version of DMEM. Additionally, it includes selenium as well as additional amino acids and vitamins. it is the only medium that lacks Iron, with potassium nitrate replacing ferric nitrate, therefore it makes it excellent for adhesive cells.
Ingredients
Iscove’s Modified Dulbecco’s Medium (IMDM) contains:
- High Buffering Capacity with High NaHCO3 as well as High HEPES
- Sodium Bicarbonate (3.02 g/L)
- 5.9 g/L HEPES
- High glucose 4.5g/L
- Non-Essential Amino Acids
- 110 mg/L Sodium pyruvate (1.0 mM)
- 15 mg/L Phenol Red
- 0.584 g/L L-glutamine
Formulation
Complete formulation of IMDM is available on our website as well as here: IMDM Formulation
References
- Plaque production by the polyoma virus. DULBECCO R, FREEMAN G. 1959 Jul;8(3):396-7. doi: 10.1016/0042-6822(59)90043-1. PMID: 13669362.
- Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes. J Exp Med. 1978 Mar 1; 147(3): 923–933. doi: 10.1084/jem.147.3.923 PMCID: PMC2184195
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- Cell Culture Media, Iscove's Modified Dulbecco's Medium (IMDM)
Chemically Defined Iscove’s Modified Dulbecco’s Medium (CD-IMDM)
- PurMa Biologics is the first company has generated Chemically Defined IMDM which does not need FBS and does not contain any animal products. This provides consistency and reproducibility of your data.
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- Sale!
- Cell Culture Media, Iscove's Modified Dulbecco's Medium (IMDM)
PurMa™ Iscove’s Modified Dulbecco’s Medium (IMDM)
- Price range: $21.62 through $557.15
- A high-buffer, high-glucose basal medium optimized for high-density, fast-growing cell lines.Suited to demanding lines such as Jurkat, HEK, COS-7, and macrophagesHigh buffering capacity and high glucose for fast growth
- Select options This product has multiple variants. The options may be chosen on the product page
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- Sale!
- Cell Culture Media, Iscove's Modified Dulbecco's Medium (IMDM)
PurMa™Iscove’s Modified Dulbecco’s Medium MAX (IMDM-MAX)
- Price range: $29.60 through $611.97
- PurMa™ Iscove’s Modified Dulbecco’s Medium MAX (IMDM‑MAX) is a premium IMDM with L alanyl Lglutamine cell culture medium optimized for demanding mammalian cells. Unlike standard IMDM, IMDM‑MAX uses stable L‑alanyl‑L‑glutamine instead of L‑glutamine. This provides a longer shelf life, stronger buffering capacity, and reduced risk of contamination, helping you achieve more consistent, reliable cell culture performance.
- Select options This product has multiple variants. The options may be chosen on the product page


