Chemically Defined Leibovitz’s L-15 Medium (CD LL-15) does not need any serum, fully synthetic and if free of any trace of animal products. Additionally, the cell growth with CD CD LL-15 is equivalent to Medium+ 10% FBS
Leibovitz's L-15 Medium was originally designed to be used in carbon dioxide (CO2) free systems. Therefore, does not need sodium bicarbonate to provide the buffering capacity. Instead, phosphates, free base amino acids, salts, and galactose maintain the physiological pH.
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