Description

Premium Fetal Bovine Serum (P-FBS)

Background

Premium Fetal Bovine Serum (P-FBS) is derived from the blood of the bovine fetus. Cell culture laboratories use FBS for growing eukaryotic especially mammalian cells. FBS contains undefined nutrition, growth factors as well. Therefore, it remains a wildly used supplement for cell culture. PurMa Biologics has developed and processes three main premium fetal bovine serums, each specialized for certain requirements in tissue culture.

Our Serum Products

PurMa Biologics produces seven types of fetal bovine serums. The three following are considered premium:

1. PurMa^TM Premium Fetal Bovine Serum (P-FBS).
2. PurMa^TM Ultra-Premium Fetal Bovine Serum (UP-FBS).
3. PurMa^TM Endotoxin Depleted Fetal Bovine Serum (EDP-FBS).

PurMa^TM Premium FBS

• All three PurMa^TM Premium FBS are of USA origin.
• Have been gamma irradiated,
• Have been heat inactivated.
• have been vigorously analyzed with the certificate of analysis.

The major differences between P-FBS and UP-FBS

• The source of the Blood and therefore:
• Significant higher growth by UP-FBS compared to P-FBS
• The depth of the analysis:

Content of PurMa^TM Premium Fetal Bovine Serum (P-FBS)

Over the years, we have tested and analyzed PurMa^TM Premium Fetal Bovine Serum (P-FBS). Please see the below table. We routinely test  every Lots order. We seriously look at the following criteria: IgG, Total Protein, Iron, Percent Iron Saturation, Inorganic Phosphorus, Glucose, Alkaline Phosphatase,  Potassium, Albumin, Blood Urea Nitrogen, Sodium, Calcium, Chloride, Total Bilirubin, Creatinine, Gamma Globulin, , Lactate Dehydrogenase, TIBC, SGOT, SGPT.

PurMa Biologics Performs Deep Analysis

Evaluated parameters  helps with the adjusting various elements , and as a result , the consistency of analysis among various Lots will highly improve.

Consistency of the ingredients among different Lots.

purifying the serum with this high stringency and robustness of the processes will make the content of serum less variable.

Analysis

Click here for the detail analysis as well as in “ Documents Tab”:Routine Pathological Analysis on PurMa Bovine and Horse Serums

References:

1. The preparation of antigenic hapten-carrier conjugates: a survey. Erlanger BF. Methods Enzymol. 1980;70(A):85-104. doi: 10.1016/s0076-6879(80)70043-5. PMID:
2. Development rates of male bovine nuclear transfer embryos derived from adult and fetal cells. Hill et al. 2000 May;62(5):1135-40. doi: 10.1095/biolreprod62.5.1135. PMID: 10775159.
3. Optimization of chemically defined cell culture media–replacing fetal bovine serum in mammalian in vitro methods. van der Valk et al. Toxicol In Vitro. 2010 Jun;24(4):1053-63. doi: 10.1016/j.tiv.2010.03.016. Epub 2010 Mar 31. PMID: 2036204.